Nursing Entrance Exam (NEX) Practice Exam

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To observe the endoplasmic reticulum in a cell, which instrument would a scientist most likely use?

Dissecting instruments

An electron microscope

The endoplasmic reticulum (ER) is a complex, membrane-bound organelle found within eukaryotic cells. To observe structures at the level of the endoplasmic reticulum, a scientist would need an instrument that provides the necessary resolution to visualize these small organelles. An electron microscope is specifically designed to achieve high magnifications and resolutions that surpass those of light microscopes, allowing for the detailed visualization of cellular components, including the ER.

Light microscopes, while useful for observing larger cellular structures, do not have the resolution to clearly view the fine details of the endoplasmic reticulum due to the limits imposed by the wavelength of visible light. Dissecting instruments are typically used for macroscopic observation and manipulation of tissues or organisms rather than for cell structures. An ultracentrifuge is a tool used to separate cellular components based on their density but does not provide any direct visual observation of structures like the ER. Thus, the electron microscope is the appropriate choice for studying the endoplasmic reticulum in detail.

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An ultracentrifuge

A light microscope

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